“Unto you, O Lord, do I lift up my soul.”
You “lift up your soul” to whatever you pray to and trust in. It is essential that when we pray and trust, we pray and trust in the living God instead of one of the gods that the religions of men offer. To trust in and pray to those gods is to lift up your soul to nothing, and there is no hope of salvation in such gods:
“Who shall ascend into the hill of the Lord? or who shall stand in His holy place? He who has clean hands, and a pure heart; who has not lifted up his soul to vanity.” (Ps. 24:3–5).